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The Centers for Disease Control and Prevention (CDC) states that these symptoms appear within 6 to 12 hours after excessive ingestion

Laser and other light-based therapies are being evaluated as potential therapies in refractory cases, although they carry the risk of worsening the condition in some cases.[] Recently, several systemic agents have been introduced for the treatment of melasma, most often as adjuncts to the established therapeutic modalities

PLoS ONE 11 , e0162192 (2016)

With injectable protocols, some patients report visible improvements in skin quality within 2-4 weeks

The most important step is a conversation with a provider who can review your goals, lifestyle, and health history before recommending a plan