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In GLP-1R -/- mice, lack of GLP-1R expression in adipocytes caused a reduction in adipogenesis, through the induction of apoptosis in pre-adipocytes by inhibiting ERK, PKC, and AKT signaling pathways (50) ( Figure 2 )
206 In addition, enzymes involved in the control of oxidative stress can be modulated by s -cysteinylation, as is the case for the metalloenzyme Cu/Zn-superoxide dismutase 1 (SOD1), which catalyses the dismutation of superoxide anions into oxygen and hydrogen peroxide
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Delayed gastric emptying could affect the timing and extent of levothyroxine absorption
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