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The unique ability of the BBB to sequester GSH from the blood circulation through its Na + -dependent GSH transporter provides a solid foundation for using the transporter as a target to develop brain-targeting drug delivery systems
Abstract Background There are concerns that glucagon-like peptide-1 receptor agonists (GLP1s) increase the risk of acute pancreatitis
SURMOUNT-4 (N=670) demonstrated that patients who completed titration and then continued maintenance tirzepatide maintained 18.2% body weight loss at 88 weeks, compared to 2.5% in the withdrawal group [11]
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