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Blimp1-T2A-Cre sperm were injected into mTmG oocytes to trace PGCs, followed by injection of a base editor mixture to introduce Trim37 ko3 into the resulting embryos (Fig

Neri D, Steele EM, Khandpur N, Cediel G, Zapata ME, Rauber F, et al

J Nutr Health Aging (2023)

Oxidative stress also activates the Kelch-like ECH-associated protein 1 (Keap1)-Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element (ARE) redox regulator pathway, releasing Nrf2 to regulate the expression of genes that control antioxidant, inflammatory and immune system responses, facilitating GSH activity

If you are considering this treatment, consult with Dr