TRIUMPH-2 (80 weeks, 12mg, 1,152 patients with type 2 diabetes): 20.8% weight loss
In acidic urine, it becomes ionized and is trapped in the tubule, increasing renal clearance
The 100 nmol/kg dose of GEP44 was tested for one day only
Back Heinrich, G, Gros, P, Lund, PK, et al (1984) 'Pre-Proglucagon Messenger Ribonucleic Acid: Nucleotide and Encoded Amino Acid Sequences of the rat pancreatic complementary deoxyribonucleic acid', Endocrinology , 115/6, 2176-81
Type 2 diabetes is far more common than type 1 diabetes and is mainly caused by resistance to the effects of the hormone insulin, which facilitates removal of glucose from the blood