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Thus, the second and a moderately conserved third cysteinyl residue (e.g
They work through mechanisms like cytokine modulation and NF-kB pathway inhibition
While adenosine triphosphate (ATP) signaling was enhanced in cultured DRG neurons treated with exendin-4, capsaicin sensitivity and calcium influx remained unaffected, suggesting GLP-1R predominantly modulating gut motility rather than pain signaling [55]
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