One placebo-controlled study examined the effect of lipoic acid on the visual capability of 80 participants of whom 12 had type 1 diabetes, 48 had type 2 diabetes, and 20 were diabetes-free
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[6] Given that retatrutide shares GLP-1 receptor activity with these agents, occasional sleep disruption is plausible, but no confirmed causal link has been established for retatrutide specifically
As SGLT-2 inhibitor use is now standard of care in people with CKD and T2D, exploring outcomes in patients receiving and not receiving SGLT-2 inhibitors is of particular interest