Funding This work was supported by Natural Science Foundation of Shandong Province (grant no
In the connection to inflammation, we showed that elevation of pro-inflammatory cytokine IL-6, increased anxiety at the lightdark test, and smaller hippocampal volume characterized at baseline (before any applied stress) those mice that become susceptible after social defeat stress (SDS) with social withdrawal and impaired transcriptomic-wide changes in ventral dentate gyrus, and that administration of LAC promoted behavioral resilience at the SDS paradigm in this susceptible phenotype [27]
Glutathione primes T cell metabolism for inflammation
Jeffrey Singer of the Cato Institute also proposed that making these drugs available without a prescription might reduce cost, increase access, and decrease stigma, but this change would likely take many years and receive pushback from clinicians
Kaidanovich-Beilin O, Milman A, Weizman A, Pick CG, Eldar-Finkelman H