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In addition, IGF-1 LR3 may promote fat breakdown by activating the MAPK pathway, leading to increased levels of free fatty acids and further exacerbating insulin resistance, forming a vicious cycle
That is why you tend to do 5 days on & 2 days off weekly.For pure fat loss, GLP-1s tend to help more in that area, which also pairs well with TRT as the T helps maintain muscle mass as you are dieting
Adenosine modulates hypoxia-induced responses in rat PC12 cells via the A2A receptor J Physiol 1998
Cox AR, McDowell S
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