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Homocysteine: A Signal, Not Just a Toxin Homocysteine is a natural byproduct of protein metabolism

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This theory also proposes that malfunction of an as yet undiscovered lactate shuttle within the NMJ may be a pathological feature of ALS, suggesting that supporting mitochondrial function may optimize lactate metabolism and combat the toxicity caused by accumulation of excess lactate

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2006;136(3 Suppl):793S-795S

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