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Key risk factors for HFpEF, such as hypertension and diabetes, are associated with endocardial and myocardial capillary endothelial abnormalities in experimental models [15, 16]

216 Epigenetic rewiring Epigenetic rewiring refers to the transformation of heritable gene expression regulation patterns without altering the DNA sequence, comprising transcription factor regulation, histone modification, and RNA epigenetic modification

Instead, apply firm pressure to the injection site for at least 2 minutes after injection and be particularly meticulous with technique
