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North America dominates the global market with a share of 46% due to the high prevalence of type 2 diabetes and obesity, advanced healthcare infrastructure, and strong presence of major pharmaceutical companies like Novo Nordisk and Eli Lilly

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indicated that GPX4 and GSH levels were decreased, and cellular iron and MDA levels were increased in a mouse model of myocardial ischemiareperfusion (MIR, ischemia 30 min and reperfusion 24 h) injury [90]

Hakuna L, Doughan B, Escobedo JO, Strongin RM (2015) A simple assay for glutathione in whole blood