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A preclinical safety study in Regulatory Toxicology and Pharmacology found BPC-157 well-tolerated with no severe toxic effects in mice, rats, rabbits, and dogs

doi: 10.1016/j.cmet.2018.06.008

Animal studies using euglycemic clamp techniques, the gold standard for insulin sensitivity assessment, confirmed that chronic AOD-9604 treatment produced no adverse effects on insulin sensitivity

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Now, of course, vascular supply arrives by capillaries, veins, and arteries