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Interestingly, in a pilot study, exposure of autologous glioma cells treated ex vivo with IGF-1R antisense oligos induced partial tumour regression in some patients with malignant astrocytoma (Andrews et al, 2001)

When a manufacturer understands these requirements and can provide the necessary documentation in advance, it helps brands avoid delays or compliance challenges during the product launch process

Larger, well-controlled clinical studies remain limited

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(PubMed) Moura FA, de Andrade KQ, dos Santos JC, Goulart MO