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It was developed at the University of Arizona by Hruby and Hadley and contains two key modifications from native -MSH: a norleucine substitution at position 4 (replacing methionine) and a D-phenylalanine substitution at position 7 (replacing L-phenylalanine)

This guide is storage context for research materials, not medical or dosing advice

In contrast to the tissue level changes observed with OCs, particularly with CHC, nano-indentation experiments revealed no change in elastic modulus and toughness which suggested that the OCs did not affect bones intrinsic material properties but likely had an effect on the macroscopic properties including overall structure or composition of the bone

95% CI, 0.77 to 0.98), stroke by 18% (HR, 0.82

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