does glp 1 increase fertility If you're on a GLP-1 and pregnancy is on your mind, you're not alone in asking what comes next. The guidance is still evolving. GLP-1s aren't currently recommended during pregnancy, the timing Can Weight Loss Injections Affect

Semaglutide is a GLP-1 agonist that is FDA approved for the treatment of type 2 diabetes and weight loss

Flamez, D

But for some people, they find these effects intolerable

Carlberg M, Nejaty J, Froysa B, Guan Y, Soder O, Bergqvist A

The GLP-1 receptor is a class B G protein-coupled receptor (GPCR) found in: Pancreatic beta cells Hypothalamic and brainstem nuclei Gastrointestinal tract Heart, kidney, and elsewhere Upon activation, it triggers multiple intracellular pathways: cAMP/PKA: enhances insulin secretion PI3K/Akt: promotes cell survival and beta cell function MAPK/ERK: involved in cell proliferation, differentiation, and potentially neuroprotective effects These pathways interact in complex ways depending on cell type, receptor density, and ligand properties