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The limited physicochemical stability and difficulty tuning their biodegradation profiles further complicate their development as viable therapeutic solutions (Muoz-Bonilla and Fernndez-Garca, 2012
| BPC-157 is a synthetic peptide derived from a naturally occurring protein in gastric juice, primarily studied for its tissue-protective and regenerative effects
Researchers examining potential neurological or cognitive effects often prefer the nasal route because it provides more direct access to the central nervous system
Even if BPC-157 survives gastric acid, pepsin and pancreatic proteases remain active in the duodenum and small intestine at physiological pH and will hydrolyze unprotected peptide bonds
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