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A data-independent (DIA) acquisition method was used, in which one full scan (3001,650 m/z , maximum ion fill time of 45 ms, normalized AGC target 300%, R = 120.000 at 200 m/z ) was followed by 66 tMS2 fragment scans of unequally spaced windows with 1 Th overlap, covering the same m/z range (fill time 22 ms, normalized AGC target 1,000%, normalized high-collision density energy of 30%, R = 15.000)

Curr Surg Rep 13 , 32 (2025)

This deficiency can lead to a variety of symptoms, including neurological problems, liver dysfunction, and hemolytic anemia

it is expressed in almost all the mammalian cells, though at much lower levels

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway