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Ditzenberger GL et al
Skinner HD, McCurdy MR, Echeverria AE, Lin SH, Welsh JW, O'Reilly MS,
Our oral peptides provide a convenient way to harness these potential benefits
Diethylester derivatives were seen to be more easily delivered into cells ( 2-Oxothiazolidine-4-carboxylic acid (OTC) is hydrolyzed to cysteine in vivo
Around 30% of patients start with bulbar symptoms, which affect the muscles used for speaking and swallowing, leading to problems like slurred speech (dysarthria), trouble swallowing (dysphagia), and twitching of the tongue muscles (Chi et al., 2013)
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