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Additionally, metformin inhibits M.tb growth, induces mitochondrial ROS production, promotes phagosomelysosome fusion in vitro, ameliorates pulmonary pathology, attenuates chronic inflammation, augments immunity, and improves the therapeutic effect of the standard anti-TB regimen in M.tb -infected mice
Furthermore, an inverse correlation was identified between the percentage of PS-positive erythrocytes and hemoglobin concentration
We thank the Shanghai Municipal Government, ShanghaiTech University and GPCR Consortium for financial support
Possible toxic consequences may not only be due to MP and NP exposure, as most commercially available particles used in studies in vivo are provided in aqueous suspensions with dispersant and conservant solvents
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