Crohns disease commonly affects the small intestine and the initial part of the large intestine, which is responsible for absorbing nutrients such as vitamin B12
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This initial period allows the body to adapt to NNMT inhibition while minimizing potential side effects
However, its essential to weigh the potential risks and side effects and consider alternative supplementation methods, such as oral supplements or patches, when appropriate
General guidelines suggest individuals under 150 pounds may start with 50-75mg daily, those between 150 and 200 pounds typically use 75mg daily as a standard protocol, and individuals over 200 pounds may need 75-100mg daily for optimal effects