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Continuous intrathecal recombinant human HGF injections exert functional recovery in non-human primate model of SCI (Aoki et al., 2019) and protect from neuronal death in ALS mice models (Ishigaki et al., 2007)
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A rigorous 2026 UK review of HGF/c-Met dopaminergic neuroprotection, the fosgonimeton SHAPE Phase 2 PDD/DLB cognitive signal, the EJS ACT-PD platform trial, Read the full review Brain Aging & MCI 29 April 2026 Dihexa for MCI & Brain Aging: 2026 UK Cognitive Decline Review Can Dihexa help mild cognitive impairment (MCI) or brain aging
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