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Mobility and function improvements become apparent
Conversely, those with inadequate response (less than 5% weight loss after 12-16 weeks at therapeutic doses) should discontinue per FDA labeling
For CKD, select a GLP-1 RA or SGLT2 inhibtor
To date, liraglutide, semaglutide, albiglutide, and dulaglutide (but not exenatide or lixisenatide) have shown superiority compared to placebo for reduction in a 3P-MACE endpoint (62)
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