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It is chemical

Why is retatrutide given once weekly

This escalation approach improves tolerability while identifying the minimum effective dose for each individual

Levtchenko EN, van Dael CM, de Graaf-Hess AC, Wilmer MJ, van den Heuvel LP, Monnens LA, Blom HJ (2006) Strict cysteamine dose regimen is required to prevent nocturnal cystine accumulation in cystinosis

G-RL revised part of the manuscript