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Common side effects of taking too much include: Nausea or an upset stomach Heartburn Diarrhea A mild "fishy" body odor (this happens when the body breaks down high doses of the supplement) Additionally, recent studies highlighted by organizations like the Cleveland Clinic have noted that gut bacteria can interact with L-carnitine to produce a compound called TMAO (trimethylamine N-oxide)

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This can include decreased stomach acid, which affects absorption, and diets low in animal products or high in processed food

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These microbiome alterations are associated with greater intestinal barrier integrity, decreased endotoxemia, and increased synthesis of short-chain fatty acids