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The optimal agent may differ by surgical context (for example, an IL-1 blocker might be more relevant in a context with high inflammasome activation like transplantation, whereas a TLR9 blocker might be ideal for cases with major tissue injury)

Because LL-37 and HBD-2 are the skin primary defense against bacterial, fungal, and viral pathogens

Activated JNK facilitates the translocation of pro-apoptotic proteins Bax and Bak to the mitochondria and simultaneously inhibits the anti-apoptotic activity of Bcl-xL, thereby indirectly triggering the mitochondrial apoptotic pathway

How Long Do IV Therapy Treatments Take