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Antiplatelet and Anticoagulation Therapy Low-dose aspirin is commonly used in ischemic CSVD, particularly in patients with lacunar infarcts

B12 adequacy is directly relevant here since B12 deficiency independently causes cognitive symptoms and mood disturbance, which is another reason the B12-containing formulation is preferred for long-term use

Without adequate collagen production and proper organization of collagen fibers, wounds heal with reduced strength and may be more prone to reopening or developing problematic scars

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GPs normally give these every 12 weeks, but the effects wear off before this and as a result the patient is left feeling sluggish and run down