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Estrogen and vaginal pH/colonization: A 2025 study assessed how estradiol (E2) levels correlate with vaginal pH and candida growth, finding that higher E2 levels can correlate with lower, more acidic pH

These doses sit well within the range tested in animal safety studies and far below levels where any toxicity was observed

Anti-Inflammatory & Cytoprotective Action Reduces levels of pro-inflammatory cytokines (TNF-, IL-6) and oxidative stress markers, supporting recovery across multiple tissue types

Firstly, Tanzeum is not recommended as a first-line treatment for patients inadequately controlled with diet and exercise

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