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Start low and slow since many people with MTHFR variants can be sensitive to B vitamins
In one clinical trial published in The New England Journal of Medicine in 2016, patients with obesity and type 2 diabetes lost an average of 10.8 pounds and lowered their A1C (a measurement of average blood sugar levels) by 1.4 percent after taking 1 mg of semaglutide for 104 weeks (8)
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This dual action gives tirzepatide an edge in effectiveness for many people
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