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To address the issue mentioned above, stimulus-responsive fluorescence imaging strategies that can activate signal light-up only in the presence of biomarkers or pathological environments can afford higher tumor-to-normal tissue ratios (T/N ratio) and real-time biological information, making the activatable modality a preferred choice for disease diagnosis and therapy evaluation [21], [22], [23], [24], [25]

Advances in Gerontology, 2024

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These conditions are also typified by loss of mitochondrial health through dysfunction of homeostatic components such as mitophagy, unfolded protein response, and the antioxidant system

Mathurin P, Louvet A, Duhamel A, Nahon P, Carbonell N, Boursier J, et al