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34, 35, 36, 37, 38, 39 However, it is unknown if GLP-1R occurs on PSCs in normal pancreas, on activated PSCs in AP or CP or if this does occur, whether the GLP-1R agonists affect the PSC signaling cascade, PSC growth or ability to release inflammatory mediators

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12.4 Severe Gastrointestinal Disease (e.g., Gastroparesis) 13