The combined primary endpoint of death from cardiovascular disease, nonfatal myocardial infarction, or nonfatal stroke occurred in 569 (6.5%) of patients in the semaglutide group versus 701 (8.0%) of patients in the placebo group, yielding a significant hazard ratio of 0.8 for a 20% relative risk reduction
Originally developed to treat diabetes, tirzepatide is safe and highly effective for long-term weight loss and weight management
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After its expiration date, the medication may not work as well for weight loss, weight maintenance, or blood sugar control