Small studies have shown inconsistent results, and theres no strong evidence that it meaningfully improves menopause or PMS symptoms.38 Taken together, these ingredients provide overlapping support for both menopause-related symptoms and PMS, which helps explain why this formula performs well across both categories even if not every component is equally well supported by research
The main practical drawbacks are cost, a more complex dosing routine, and the fact that you are adding Dihexa, the least-evidenced and least safety-characterized component
Nrf2 has been shown to negatively regulate stimulator of interferon genes (STING) expression by decreasing STING mRNA stability, thus indicating an association in antiviral sensing 66
The theory is plausible given BPC-157's mechanisms, but remains unproven
J Med Food 8:4752, PMID: 15857209 Singh A, Garg V, Gupta S, Kulkarni SK (2002) Role of antioxidants in chronic fatigue syndrome in mice