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These factors include aging, poor diet, stress, pollution, and certain medical conditions

While large-scale randomized controlled trials (RCTs) have focused on higher-dose protocols for regulatory approval, a growing number of physicians are reporting excellent results at significantly lower doses , especially in individuals who are metabolically healthy or seeking lifestyle optimization rather than aggressive weight loss

For those also making supportive lifestyle changes like changing their diet and increasing their exercise, progress often feels more noticeable during this time