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Here are a few reasons for this: Proteolysis (protein digestion): Protein digestion is likely to be impaired in hypothyroidism, but tends to be accelerated in hyperthyroidism

In Vitro and in Vivo Anti-Diabetic Effects of Anthocyanins from Maqui Berry (Aristotelia chilensis)

Even more concerning, some supplements that claim to promote weight loss may pose real health risks

This also applied to another five ongoing studies identified (Supplementary Section 3)