Li ZY, Zhang N, Wen S, Zhang J, Sun XL, Fan XM et al (2017) Decreased glucagon-like peptide-1 correlates with abdominal pain in patients with constipation-predominant irritable bowel syndrome
[2] Patients should also seek medical review if constipation significantly impacts quality of life or if they find themselves increasingly reliant on stimulant laxatives
However, there may still be some issues in practical applications that require further research and resolution
References (this section): Eli Lilly: notes GI side effects commonly reported and often during dose escalation (Phase 2 summary) NEJM (2023): safety/adverse events in Phase 2 publication Is retatrutide FDA approved
Additionally, certain medical conditions, including cystic fibrosis and HIV/AIDS, can also lead to reduced glutathione levels