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The 17 non-RCTs, included 21 independent intervention groups, of which the majority were CR (n = 18), followed by CREX (n = 2) and EX (n = 1)

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This maintains skin firmness and elasticity

Multi-dose pens (used for multiple injections) have specific in-use storage periods after first use: Semaglutide (Ozempic) : After first use, may be stored in the refrigerator or at room temperature (up to 86F/30C) for up to 56 days [1] [2] Liraglutide (Victoza) : After first use, can be stored refrigerated or at room temperature (59-86F/15-30C) for 30 days Liraglutide (Saxenda) : After first use, can be stored refrigerated or at room temperature (59-86F/15-30C) for 30 days Exenatide (Byetta) : After first use, store at room temperature (68-77F/20-25C) for up to 30 days

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