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DHODH Dihydroorotate dehydrogenase (DHODH) is a flavin-dependent mitochondrial enzyme that catalyzes the fourth step in the de novo synthesis of pyrimidine nucleotides and is a key enzyme in pyrimidine synthesis
Vitamin B12 , also known as cobalamin, is essential for red blood cell formation, DNA synthesis, and neurological function
Nat Neurosci 22:16871695
Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver
Moreover, additional pathogens may emerge, following the translocation of gut bacteria in the blood through an inflamed, damaged gut mucosa (as discussed later)
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