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Fever or signs of infection Severe abdominal pain Unexplained weight loss No bowel movement for more than 5 days Blood in stools Bleeding during bowel movements These symptoms can be serious and may indicate complications such as gastrointestinal bleeding, bowel obstruction, or other conditions that require immediate medical evaluation

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Overeating and abnormal feeding rhythm contribute to development of obesity 3,4

GLP1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities