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Its stable in human gastric juice, unlike other peptides, allowing it to act directly in the gastrointestinal (GI) tract

We evaluated glucose excursion after intraperitoneal injection of pyruvate to further evaluate the cell-specific roles of DPP4 in regulating HGP

Certain nutrients and food components can trigger GLP-1 secretion from your intestinal L-cells

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Another factor to consider is whether the potential long term benefits, including weight loss or possible disease improvement, would require continued use of GLP-1 agonist in addition to other IBD treatment options, as this can represent an additional financial or emotional burden on patients.