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FDA approval and testing Wegovy (for weight management) and Ozempic (for type 2 diabetes) went through years of clinical trials involving thousands of participants

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2 Thats the enzyme targeted by NSAIDs, which causes pain and inflammation

These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

Harsh chemicals or excessive scrubbing can create irritation, which will trigger more inflammation and make dark spots darker