The underlying mechanisms, including modulation of redox-sensitive signaling pathways (e.g., Nrf2, AMPK) and apoptotic regulators (Bax, Bcl-2, p53), were also investigated
Other data generated are available from the corresponding author upon reasonable request
Conversely, male patients often exhibit normal overall ROS levels in their lymphocytes but show profound, specific mitochondrial lipid oxidative damage
It is produced mainly by the liver and is involved in multiple biological processes such as When glutathione levels decrease, the skin becomes dull, pigmented, uneven, and more prone to oxidative damage
As an endogenous substance naturally produced by the body, glutathione does not typically cause serious adverse effects when taken orally