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L.GardnerJ.DawsonG.et al (2003)

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Ein einfach zu adressierender Risikofaktor fr eine Myokarditis scheint die schnelle Aufdosierung von Clozapin zu sein, sodass in diesen Fllen besondere Vorsicht geboten ist

GSH depletion causes ferroptosis in RPE cells To evaluate the mechanism of cell death in GSH-depleted cells, we treated RPE cells with various cell death pathway inhibitors including ferroptosis inhibitors ferrostatin-1 (Fer-1, 8 M), liproxstatin-1 (Lip-1, 600 nM), iron chelator deferoxamine (DFO, 80 M), pan-caspase inhibitor z-VAD-fmk (30 M) to inhibit apoptosis, autophagy inhibitor 3-methyladenine (3-MA, 10 mM), and lysosomal inhibitor bafilomycin A1 (Baf-A1, 75 nM)