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Westerbacka J, Kolak M, Kiviluoto T, Arkkila P, Siren J, Hamsten A, Fisher RM, Yki-Jarvinen H (2007) Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects
Thus, the transition from "physiological" to "pathological" fibrosis is driven by impaired apoptosis of myofibroblasts, as well as excessive ECM deposition and accumulation, resembling a persistent wound-healing response
Potential laboratory applications include investigations into: Cellular Signaling Researchers study how peptide interactions influence communication between cells and intracellular signaling pathways
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Explaining osteomyelitis and prosthetic joint infections (PJI) in terms of biofilmA review
