Breaks make sense for users experiencing treatment plateau where benefits cease increasing despite continued application suggesting diminishing returns from ongoing use, comfortable with some benefit decline during off periods accepting fluctuation in skin quality, budget-conscious seeking to minimize annual treatment costs through intermittent purchasing, philosophically preferring avoiding indefinite dependency on any skincare product, planning life changes incompatible with consistent application (extended travel, relocation, financial shifts), and wanting to assess whether improvements prove durable or require continuous maintenance before committing to indefinite treatment
Pancreatitis risk is another consideration
Makhro A, Hnggi P, Goede JS, Wang J, Brggemann A, Gassmann M, et al
All descriptions are based on publicly available information from the company's official website and general industry sources
Metal coordination Forms a blue copper complex through defined ligand interactions