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Mood and Mental Health Changes Semaglutide is not just a weight-loss medication
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Among participants who had prediabetes at baseline, around 71 percent returned to normoglycaemia by week 64, compared with roughly 33 percent on placebo (Wharton et al., 2025)
In the 68-week Phase 3 TRIUMPH-4 trial , adults with obesity and at least one weight-related medical problem who took 9 mg of retatrutide lost an average of about 26% body weight, while those taking 12 mg retatrutide lost an average of nearly 29%
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Kiyosue A, Dunn JP, Cui X, Hickey A, Hirase T, Imaoka T, et al
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