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Oxidative stress plays a prominent role in SARS-CoV-2 infection following recognition of the viral S-protein by angiotensin converting enzyme-2 receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production

Glutathione levels also decrease as we age and our need for supplemental glutathione increases significantly

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Alongside the immune system , it supports white blood cell function and helps keep the body's response to threats measured and effective