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Digestive issues: GLP-1s can cause nausea, vomiting, diarrhea, or constipationsymptoms that may be worsened during fasting

1) (Marso et al 2016

Sin embargo, a pesar de la gran cantidad de evidencia acumulada en los aos siguientes, no se le dio mayor importancia hasta que se conoci que alteraciones en mecanismos renales de regulacin de la glucosa estaban involucradas en la patogenia de la DM2

Glucagon-like peptide 1 receptor agonist ameliorates the insulin resistance function of islet cells via the activation of PDX-1/JAK signaling transduction in C57/BL6 mice with high-fat diet-induced diabetes

Satish Garg of the Barbara Davis Center for Diabetes in Colorado and convened by diaTribe