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In 2021, Kishimoto et al., in a double-blind, placebo-controlled clinical trial, evaluated the anti-inflammatory effects of curcuRouge for 4 weeks on systemic inflammation in adults over 60 years of age in Japan [62]

151,152 H 2 S and cancer: beyond disturbed metabolism In addition to the energetic stimulus afforded by low H 2 S concentrations, the link between the adaptability of cancer cells to an evolving and challenging environment and enhanced H 2 S metabolism extends to adaptation to hypoxia, antioxidant capacity, neoangiogenesis, cell cycle regulation, apoptosis evasion and chemoresistance

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Insulin can effectively promote local skull bone formation by increasing the number of osteoblasts and osteoid surface area in the mouse skull [13], and can regulate the activity of osteoclasts [14]

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