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This creates a devastating feedback loop: mast cells release histamine, which causes systemic inflammation

Bimagrumab vs optimized standard of care for treatment of sarcopenia in community-dwelling older adults: a randomized clinical trial

It represents a fundamental shift toward more sophisticated, mechanistically-informed approaches to metabolic disease treatment that address the full complexity of these disorders rather than targeting isolated pathways in isolation

The data here is preliminary but intriguing

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